2024 Karyophilic protein

Karyophilic protein

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Webb6 okt. 2016 · Feldherr CM, Kallenbach E, Schultz N. Movement of a karyophilic protein through the nuclear pores of oocytes. J Cell Biol. 1984 Dec; 99 (6):2216–2222. [PMC free article] Fields AP, Kaufmann SH, Shaper JH. Analysis of the internal nuclear matrix. Oligomers of a 38 kD nucleolar polypeptide stabilized by disulfide bonds. Webbkaryophilic proteins Source: Oxford Dictionary of Biochemistry and Molecular Biology Author(s): Richard CammackRichard Cammack, Teresa AtwoodTeresa Atwood, Peter …

Enhanced intracellular mobility and nuclear accumulation of DNA ...

Webb14 apr. 1995 · Physiological evidence has indicated that karyophilic proteins are complexed in the cytoplasm upon active nuclear import ; however, no such complex … WebbIntracellular transport of karyophilic cargos comprises translocation to the nuclear envelope and subsequent nuclear import. Small cargos such as isolated proteins can reach the nuclear envelope by diffusion but movement of larger structures depends on active translocation, typically using microtubules. filling new propane tank

A karyophilic protein forms a stable complex with cytoplasmic

WebbThe inhibitory effect on nuclear protein uptake was monitored by co-injection of the karyophilic protein nucleoplasmin. When injected by itself early in mitosis, nucleoplasmin became sequestered into the daughter nuclei as they entered telophase. In contrast, nucleoplasmin was excluded from the daughter nuclei in the presence of WGA or … Webb1 mars 2005 · Plasmids Enhanced Intracellular Mobility and Nuclear Accumulation of DNA Plasmids Associated with a Karyophilic Protein DOI: Source Authors: Adi Mesika Vladimir Kiss Weizmann Institute of Science... WebbKaryophilic Proteins: Polypeptides Synthesized in vitro Accumulate in the Nucleus on Microinjection into the Cytoplasm of Amphibian Oocytes Proc. Natl. Acad. Sci. USA Vol. … filling news

3840 - Gene ResultKPNA4 karyopherin subunit alpha 4 [ (human)]

Shuttling proteins go both ways - ScienceDirect

WebbThe study of the mechanisms by which proteins are selectively accumulations in the cell nucleus has lagged behind the study of other transport processes, such as those that … WebbThe probes used in these experiments were (a) mAb-414, which cross-reacts with Xenopus nucleoporins containing O-linked N-acetyl glucosamines; (b) wheat germ agglutinin, a transport inhibitor; and (c) nucleoplasmin, a transport substrate. filling new pool with waterWebbMoreover, two expression level regulatory signals (ELRSs) and two DNA binding signals (DBSs) were also mapped to the N terminus of the protein and overlapped with the two NLSs. The ability of CP to bind DNA, coupled with the karyophilic nature of this protein, strongly suggests that it may be responsible for nuclear targeting of the viral genome. groundguard

"Webb9 juli 1996 · Here we report the mapping of karyopherin beta's binding sites both for Ran-GTP and for karyopherin alpha. We discovered that karyopherin beta's binding site for Ran-GTP shows a striking sequence similarity to the cytoplasmic Ran-GTP binding protein, RanBP1. " - Karyophilic protein

Karyophilic protein

A plant in vitro system for the nuclear import of proteins

Webb1 jan. 1995 · Two proteins of 60-62 kDa were the predominant substrates phosphorylated by both protein kinase C and protein kinase A under conditions wherein nuclear transport was restored. Our results suggest a requirement for phosphorylation of one or more proteins for binding of a karyophilic protein at the nuclear envelope. Webb1-31. (canceled) 32.A composition comprising a pharmaceutically acceptable carrier and an importin alpha-selective nuclear transport modifier (NTM) comprising the amino acid sequence SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 20, SEQ ID NO: 25, SEQ ID NO: 26, SEQ ID NO: 27, SEQ ID NO: 28, or SEQ ID NO: 29 in an amount …

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Webb第8题： cross-linking protein (交联蛋白) 正确答案: 具有两个或两个以上同肌动蛋白结合的位点，能够使两个或多个肌动蛋白纤维产生交联，使细胞内的肌动蛋白纤维形成网络结构。有些交联蛋白是杆状的，能够弯曲，由这种交联蛋白形成的网络结构具有相当的弹性，因而能够抵抗机械压力。 WebbIt consists of karyophilic protein and four proteins of 54, 56, 66, and 90 kDa. In our reconstitution experiments, a complex with 54 and 90 kDa proteins is capable of targeting karyophiles to the nuclear pores. The selective nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear location signals (NLSs)

Webb24 juli 1995 · We recently showed that a karyophilic protein forms a stable complex, termed nuclear pore-targeting complex (PTAC), with cytoplasmic components … WebbKaryopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Webb1 jan. 1987 · Molecular characterization of a karyophilic, histone-binding protein: cDNA cloning, amino acid sequence and expression of nuclear protein N1/N2 of Xenopus laevis January 1987 The EMBO Journal 5(13 ... Webb1 juli 1990 · Colloidal gold stabilized with BSA was used to study diffusion, whereas transport was investigated using gold particles coated with nucleoplasmin, a karyophilic Xenopus oocyte protein. The gold tracers were microinjected into the cytoplasm, and subsequently localized within the cells by electron microscopy.

Webb2 sep. 1997 · The karyophilic properties of the HIV-1 nucleoprotein complex facilitate infection of nondividing cells such as macrophages and quiescent T lymphocytes, and allow the in vivo delivery of transgenes by HIV-derived retroviral vectors into terminally differentiated cells such as neurons. Although the viral matrix (MA) and Vpr proteins …

WebbIt consists of karyophilic protein and four proteins of 54, 56, 66, and 90 kDa. In our reconstitution experiments, a complex with 54 and 90 kDa … filling night snacksWebb细胞生物学必背问答题(一).pdf,精品资料细胞生物学必背问答题(一) 精品资料细胞生物学必背问答题 (一) 1、为什么说细胞是生命活动的基本单位？ ① 细胞是构成有机体的基本单位。 ② 细胞是代谢与功能的基本单位。 ③ 细胞是有机体生长和发育的基础。 ④ 细胞是繁殖的基本单位，是遗传的桥梁。 filling nan values with mean ground guiding proceduresWebb14 apr. 1995 · It consists of karyophilic protein and four proteins of 54, 56, 66, and 90 kDa. In our reconstitution experiments, a complex with 54 and 90 kDa proteins is … filling new vacanciesWebbEnhanced intracellular mobility and nuclear accumulation of DNA plasmids associated with a karyophilic protein Authors Adi Mesika 1 , Vladimir Kiss , Vlad Brumfeld , … ground guiding signalsWebb1 dec. 1984 · It has recently been shown that large karyophilic proteins are transported across the nuclear envelope in amphibian oocytes. In consideration of this, the present … ground guide signal close upWebbThe findings suggest that nuclear proteins contain in their molecular structure a signal that enables them to accumulate in the nucleus, which is absent in proteins such as actin, which are similarly abundant in both nucleus and cytoplasm. 197 Movement of a karyophilic protein through the nuclear pores of oocytes ground guide signals