Traf2 molecular weight
Splet21. mar. 2024 · TRAF2 (TNF Receptor Associated Factor 2) is a Protein Coding gene. Diseases associated with TRAF2 include Lymphoma, Mucosa-Associated Lymphoid Type and Leukodystrophy, Hypomyelinating, 3 . Among its related pathways are MyD88 dependent cascade initiated on endosome and TNFR1 Pathway . Splet01. apr. 2024 · KO cells expressing the C-terminal portion of TRAF2 (hereinafter referred to as Cterm) were generated by stable transfection with an expression vector encoding residues 310–501 of human TRAF2 (theoretical molecular weight: 21.71 kDa). WT, KO and Cterm cells had similar morphological features and proliferation rates (data not shown).
Traf2 molecular weight
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SpletTRAF2 is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-κB. The protein complex formed by TRAF2 and TRAF1 interacts with the IAP family members cIAP1 and cIAP2, and functions as a mediator of the … SpletImmunogen: Human TRAF2 aa. 93-199 Application: Western blot (Routinely Tested) Target Molecular Weight: 53 kDa Concentration: 0.5 mg/ml RRID: AB_397143 Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. Regulatory Status: RUO View All Formats Preparation And Storage
SpletImmunogen: Human TRAF2 aa. 93-199 Application: Western blot (Routinely Tested) Target Molecular Weight: 53 kDa Concentration: 0.5 mg/ml RRID: AB_397143 Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. Regulatory Status: RUO View All Formats Preparation And Storage Splet01. apr. 2024 · TRAF2 is the most extensively studied member of the TRAF family (Bradley and Pober, 2001, Borghi et al., 2016). TRAF2 is recruited to the membrane through the interaction of its TRAF domain with activated receptors, including Tumor Necrosis Factor Receptor 2 (TNFR2), CD30, CD40, Ox40 and others.
SpletTRAF2 homotrimer bound a locked trimeric CD40 cytoplasmic domain (iZip-CD40) by surface plasma resonance with a K D of 2.5 μM, 12-fold higher affinity than monomeric TRAF2 used in the same experiment. It is important that the TRAF molecules have relatively low affinity for the receptor cytoplasmic domains as too strong an interaction of TRAFs ... SpletMolecular weight (Da) 55728.19 Theoretical pI 7.72 TRAF2 Protein Structure STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 5-RESIDUE CD40 PEPTIDE Deposited 1999-09-07 Released: 2000-03-29 Deposition Author (s) Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H. Organism (s) Homo sapiens Expression System …
SpletWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain Specific) (D3V2A) mAb (HRP Conjugate) as a secondary antibody to minimize interference produced by denatured mouse heavy chain.
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms complexes with other TRAF proteins. TRAF2 is required for TNF-alpha-mediated activation of MAPK8/JNK … kfc australia feedback surveyislcollective ferienSplet13. jun. 2013 · Furthermore, A20 is capable of targeting an associated signaling molecule such as TRAF2 to the lysosomes for degradation, a process that does not require A20 ubiquitin modifying activity . Notably, A20 −/− and MCPIP1 −/− mice spontaneously develop severe inflammatory syndrome [ 219 , 220 ], while CYLD −/− and Usp25 −/− mice are ... islcollective francaisSpletNational Center for Biotechnology Information isl collective days of the weekSplet12. sep. 2024 · In polymer chemistry, the width of the distribution of molecular weights is described by the dispersity (Ð, also called, in older texts, the polydispersity or the polydispersity index, PDI). The dispersity of a polymer sample if often between 1 and 2 (although it can be even higher than 2). The closer it is to 1, the narrower the distribution. isl collective daz uhrzeitSpletThe protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. kfc at westbourne road huddersfieldSpletbody weight and fat mass than wild-type mice, consistent with the metabolic role of Nur77 (Chao et al., 2007, 2009; Chen et al., 2015; Perez-Sieira et al., 2013). Importantly, Nur77 / mice were resistant to the anti-obesity effects of celastrol, as celastrol showed only about 4% inhibition on body weight of isl collective en anglais