Web21 Mar 2024 · UHRF1 (Ubiquitin Like With PHD And Ring Finger Domains 1) is a Protein Coding gene. Diseases associated with UHRF1 include Colorectal Cancer and Cerebellar … Web5 Jan 2016 · Thus, UHRF1 is a key regulator of DSB repair choice, which is separate from its role in heterochromatin formation and epigenetic regulator. DNA double-strand breaks (DSBs) pose a serious hazard...
UHRF1 Promotes Cell Growth and Metastasis Through Repression …
WebFigure 1.uhrf1 and dnmt1 loss causes DNA methylation loss in zebrafish livers.(A) Slot blot of genomic DNA extracted from pools of 5 dpf uhrf1 −/− and dnmt1 −/− mutant and WT siblings livers. (B) Quantification of 5-MeC measured by slot blot normalized to double stranded DNA (dsDNA). Each dot represents one clutch. *p < 0.05 and **p < 0.005 … Web6 Sep 2024 · UHRF1 is most known for its role in maintaining DNA methylation [ 11, 12 ]. UHRF1 is overexpressed in different cancers that frequently present RB1 mutations, including lung, breast, bladder,... humanitarian westjet
Unchanged PCNA and DNMT1 dynamics during replication in DNA …
Web18 May 2024 · The anti-HBP1 (sc-515281), β-actin (sc-47778), MIF (sc-271631) and anti-UHRF1 (ab57083) antibodies were purchased from Santa Cruz Biotechnology and Abcam, respectively. The Co-IP kit (26149 Pierce) was purchased from Pierce and the EasySep™ Human T Cell Isolation kit was obtained from Stem Cell (cat. no. 17951, Stem Cell). Web8 Sep 2013 · The RING finger domain protein Uhrf1 has an essential role in maintaining patterns of DNA methylation during replication by recruiting the DNA methyltransferase Dnmt1 to hemi-methylated DNA... WebUHRF1 (D6G8E) Rabbit mAb recognizes endogenous levels of total UHRF1 protein. This antibody does not cross-react with UHRF2 protein. This antibody may recognize a non … hollard specialist insurance